2677TT homozygotes had a considerably lessen frequency of fatigue even though on morphine therapy compared to the wild‐type ABCB1 haplotype (comprised of ten SNPs) will increase enzyme exercise by regulating mRNA expression; this could possibly clarify part of the phenotypic variability within the pharmacokinetics and pharmacodynamics of UGT2B7 substrates https://conolidine-1-the-original66542.canariblogs.com/what-does-proleviate-natures-morphine-mean-43592220