Epidural clonidine used as an adjunct to local anesthetics has three distinctive mechanisms of action. Initially, the stimulation of alpha-two-receptors while in the dorsal horn lowers discomfort transmission. Secondly, clonidine could potentially cause area vasoconstriction that boundaries vascular elimination of area epidural anesthetics. Jun 10, 2024 · If clonidine https://harryv826mlk8.livebloggs.com/profile