Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors inside the central nervous system, conolidine modulates alternate molecular targets. A Science Developments research located that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By ... https://knoxrjagv.bligblogging.com/39737433/what-does-alternative-natural-pain-relief-to-replace-traditional-painkillers-mean